李娜,1976年8月出生,博士,研究员,主要研究方向为园艺作物器官发育调控的分子机制。
◆教育背景
1995.09-1999.07,东北师范大学,生物技术专业,学士学位
2001.09-2004.07,中国科学院遗传与发育生物学研究所,遗传学专业,硕士学位
2004.09-2008.01,中国科学院遗传与发育生物学研究所,发育生物学专业,博士学位
◆工作经历
2020.01至今,365体育官方唯一入口,研究员
2019.06至今,365体育官方唯一入口,校聘教授
2015.01-2019.05,中国科学院遗传与发育生物学研究所,副研究员
2013.09-2013.12,英国John Innes Centre,访问学者
2011.05-2014.12,中国科学院遗传与发育生物学研究所,助理研究员
2008.11-2011.04,荷兰Wageningen大学,博士后
◆荣誉称号
2020年,365体育官方唯一入口“高峰人才”
2019年,365体育官方唯一入口“太行学者”三层次
◆教学情况
本科课程,分子生物学专题与实践
博士课程,分子生物学研究专题
留学生课程,高级分子生物学专题
留学生课程,蔬菜seminar
留学生课程,蔬菜生物技术与品种改良
◆科研项目
国家自然科学基金面上项目,LONG8及其互作蛋白LGIP1调控水稻籽粒大小的分子机理研究,2019/01-2022/12,第1(59万元)
国家自然科学基金国际(地区)合作与交流项目项目,两个核心生长调节因子的下游分子途径研究,2019.01-2021.12,第2(200万元)
国家自然科学重大研究计划,水稻籽粒大小调控的分子遗传网络解析,2018.01-2019.12,第6(450万元)
国家重点研发项目,主要农作物品质性状形成的分子基础,2016.1-2020.12,任务负责人(119万元)
转基因重大专项,高产性状关键基因克隆及功能验证,2016.1-2018.12,任务负责人(70.09万元)
国家自然科学重大研究计划,植物生长素调控种子和器官大小的分子机理研究,2015.01-2015.12,第2(85万元)
国家自然科学基金青年基金项目,拟南芥DA2基因调控种子和器官大小的分子机制,2014/01-2016/12,第1(23万元)
留学回国人员科研启动基金,第46批,第1(3万元)
◆授权专利
ZL 2014 8 00 197. 9(中国),调节植物中的种子和器官大小的方法,李云海;夏天;李娜;杰克·杜梅尼尔;迈克尔·贝文,申请日期:30 July 2014,授权公告日:2019年11月26日
No 033454(Eurasian),Methods of modulating seed and organ size in plants,Li Yunhai, Xia Tian, Li Na, Dumenil Jack, Bevan Michael,申请日期:30 July 2014,授权日期:2019年10月31日
US 10329577 B2(USA),Methods of modulating seed and organ size in plants,Yunhai Li, Tian Xia, Na Li, Jack Dumenil, Michael Bevan,申请日期:2014年7月30日,授权日期:2019年6月25日
No 119645(Ukraine),A method of increasing the yield of plants,Yunhai Li, Tian Xia, Na Li, Jack Dumenil, Michael Bevan,申请日期:2016年8月,授权日期:2019年7月25日
◆论文论著 (*co-first author)
Li, N.*, Xu, R.*, and Li, Y. (2019). Molecular networks of seed size control in plants. Annual Review of Plant Biology 70, 435–63
Xu, R.*, Li, N.*, Li, Y. (2019) Control of grain size by G-protein signaling in rice. Journal of Integrative Plant Biology 5, 533-540
Li, N.*, Liu, Z.*, Wang, Z., Ru, L., Gonzalez, N., Baekelandt, A., Pauwels, L., Goossens, A., Xu, R., Zu, Z., Inze, D. and Li, Y. (2018). STERILE APETALA modulates the stability of a repressor protein complex to control organ size in Arabidopsis thaliana. PLoS Genetics 14, e1007218
Li, N., Xu, R., Duan, P. and Li, Y. (2018). Control of grain size in rice. Plant Reproduction. DOI:10.1007/s00497-018-0333-6
Li, S., Xu, R., Li, A., Liu, K., Gu, L., Li, M., Zhang, H., Zhang, Y., Zhuang, S., Wang, Q., Gao, G., Li, N., Zhang, C., Li, Y., Yu, B. (2018). SMA1, a homolog of the splicing factor Prp28, has a multifaceted role in miRNA biogenesis in Arabidopsis. Nucleic Acids Research. DOI:10.1093/nar/gky591 11.56
Xu, R., Duan, P., Yu, H., Zhou, Z., Zhang, B., Wang, R., Li, J., Zhang, G., Zhuang, S., Lyu, J., Li, N., Chai, T., Tian, Z., Yao, S., Li, Y. (2018). Control of Grain Size and Weight by the OsMKKK10-OsMKK4-OsMAPK6 Signaling Pathway in Rice. Molecular Plant. DOI:10.1016/j.molp.2018.04.004
Xu, R., Yu, H., Wang, J., Duan, P., Zhang, B., Li, J., Li, Y., Xu, J., Lyu, J., Li, N., Chai, T. (2018). A Mitogen-Activated Protein Kinase Phosphatase influences grain size and weight in rice. Plant Journal. doi: 10.1111/tpj.13971
Dong, H.*, Dumenil, J.*, Lu, F.H.*, Li, N.*, Vanhaeren, H., Naumann, C., Klecker, M., Prior, R., Smith, C., McKenzie, N., et al. (2017). Ubiquitylation activates a peptidase that promotes cleavage and destabilization of its activating E3 ligases and diverse growth regulatory proteins to limit cell proliferation in Arabidopsis. Genes & Development 31, 197-208.
Huang, K., Wang, D., Duan, P., Zhang, B., Xu, R., Li, N., Li, Y. (2017). WIDE AND THICK GRAIN 1, which encodes an otubain-like protease with deubiquitination activity, influences grain size and shape in rice. Plant Journal 91, 849-860.
Li, N., and Li, Y. (2016). Signaling pathways of seed size control in plants. Current Opinion in Plant Biology 33, 23-32
Xu, Y., Jin, W., Li, N., Zhang, W., Liu, C., Li, C., and Li, Y. (2016). UBIQUITIN-SPECIFIC PROTEASE14 Interacts with ULTRAVIOLET-B INSENSITIVE4 to Regulate Endoreduplication and Cell and Organ Growth in Arabidopsis. The Plant Cell 28, 1200-1214.
Wang, Z., Li, N., Jiang, S., Gonzalez, N., Huang, X., Wang, Y., Inze, D., and Li, Y. (2016). SCF(SAP) controls organ size by targeting PPD proteins for degradation in Arabidopsis thaliana. Nature Communications 7, 11192.
Li, N., and Li, Y. (2015). Maternal control of seed size in plants. Journal of Experimental Botany 66, 1087-1097
Du, L.*, Li, N.*, Chen, L., Xu, Y., Li, Y., Zhang, Y., and Li, C. (2014). The ubiquitin receptor DA1 regulates seed and organ size by modulating the stability of the ubiquitin-specific protease UBP15/SOD2 in Arabidopsis. The Plant Cell 26, 665-677
Li, N., and Li, Y. (2014). Ubiquitin-mediated control of seed size in plants. Frontiers in Plant Science 5, 332
Xia, T.*, Li, N.*, Dumenil, J.*, Li, J., Kamenski, A., Bevan, M.W., Gao, F., and Li, Y. (2013). The Ubiquitin Receptor DA1 Interacts with the E3 Ubiquitin Ligase DA2 to Regulate Seed and Organ Size in Arabidopsis. The Plant Cell 25, 3347-3359
Fabregas, N., Li, N., Boeren, S., Nash, T.E., Goshe, M.B., Clouse, S.D., de Vries, S., and Cano-Delgado, A.I. (2013). The BRASSINOSTEROID INSENSITIVE1- LIKE3 Signalosome Complex Regulates Arabidopsis Root Development. The Plant Cell 25, 3377-3388
Peng, Y., Ma, W., Chen, L., Yang, L., Li, S., Zhao, H., Zhao, Y., Jin, W., Li, N., Bevan, M.W., Li, X., Tong, Y., and Li, Y. (2013). Control of root meristem size by DA1-related protein 2 in Arabidopsis thaliana. Plant Physiology 161, 1542-1556
Smaczniak, C.*, Li, N.*, Boeren, S., America, T., van Dongen, W., Goerdayal, S.S., de Vries, S., Angenent, G.C., and Kaufmann, K. (2012). Proteomics-based identification of low-abundance signaling and regulatory protein complexes in native plant tissues. Nature Protocols 7: 2144-2158
Li, S., Liu, Y., Zheng, L., Chen, L., Li, N., Corke, F., Lu, Y., Fu, X., Zhu, Z., Bevan, M.W., and Li, Y. (2012). The plant-specific G protein gamma subunit AGG3 influences organ size and shape in Arabidopsis thaliana. New Phytologist 194: 690-703.
Mravec, J., Petrášek, J., Li, N., Boeren, S., Karlova, R., Kitakura, S., Pařezová, M., Naramoto, S., Nodzyński, T., Dhonukshe, P., Bednarek, S., Zažímalová, E., Vries, S., and Friml, J. (2011). Cell plate restricted association of DRP1A and PIN proteins is required for cell polarity establishment in Arabidopsis. Current Biology 21: 1055-1060
Li, N.*, Yuan, L.*, Liu, N., Shi, D., Li, X., Tang, Z., Liu, J., Sundaresan, V., and Yang, W.C. (2009). SLOW WALKER2, a NOC1/MAK21 homologue, is essential for coordinated cell cycle progression during female gametophyte development in Arabidopsis. Plant Physiology 151: 1486-1497
◆团队和平台
省部共建华北作物改良与调控国家重点实验室
蔬菜分子染色体工程与新品种选育创新团队
河北省“巨人计划”创新团体
河北省蔬菜产业协同创新中心
河北省蔬菜种质创新与利用重点实验室
◆学术会议
参加国际学术会议8次,全国性学术会议10次,省级学术会议5次,其他学术会议10次。
◆联系方式
电子邮件:yyln@hebau.edu.cn